Study Suggests New Ways to Prevent Costly Cattle Disease

Dr. Dale Woerner
Professor, Cargill Endowed Professorship in Meat Science, Department of Animal and Food Sciences

Year Awarded  2023

FFAR award amount   $300,000

Total award amount   $633,462

Location   Lubbock, TX

Matching Funders   Genus ABS, Hy-Plains Feedyard, LLC, Texas Tech University, Veterinary Research & Consulting Services, LLC

Grantee Institution   Texas Tech University

  • Production Systems

Liver abscesses are a costly problem for cattle and producers. This research determined that liver abscesses in beef-on-dairy crossbred cows are linked to changes in the rumen, the largest compartment of a cow’s stomach, not inherited traits. The study suggests that breeding is unlikely to reduce abscesses, while management practices that improve rumen health may help. Blood tests also predicted abscesses with 80% accuracy, offering opportunities for earlier detection and prevention. The findings could improve animal welfare and benefit beef producers’ bottom lines.

Detecting A Costly Cattle Disease

Liver abscesses are a serious health and economic concern for beef producers. The disease cost the beef cattle industry an estimated $256 million annually due to slower growth, reduced feed efficiency and losses at processing. The condition is difficult to detect in living cattle and often remains undiscovered until processing. Additionally, existing prevention methods, including antibiotics and vaccines, are not always effective.

Looking Beyond Genetics for Answers

Seeking better solutions, researchers led by Dr. Dale Woerner of Texas Tech University analyzed carcass, blood and genetic data from 1,984 *beef-on-dairy crossbred heifers. The study, funded by the International Consortium for Antimicrobial Stewardship in Agriculture (ICASA), found little evidence that susceptibility to liver abscesses is genetically inherited. Instead, the condition is associated with changes in the rumen, the first and largest chamber of a cow’s four-chamber stomach, that may allow harmful bacteria to reach the liver.

The study also revealed a potential path toward earlier detection, as well as new clues about the most serious cases. Patterns in the animals’ blood predicted the presence of abscesses with 80% accuracy in the study. Researchers also detected higher prevalence of two harmful bacteria, Trueperella pyogenes and Salmonella enterica, in cattle with severe abscesses.

Dr. Dale Woerner

For too long, liver abscesses have been a costly surprise discovered during processing. With high costs and tight margins challenging U.S. beef operations, earlier detection and prevention could drastically improve producers’ bottom lines, cattle health and potentially reduce the need for antibiotics.

Dr. Dale Woerner
Professor, Cargill Endowed Professorship in Meat Science, Department of Animal and Food Sciences, Texas Tech University

Why it Matters for U.S. Producers

The findings reveal that selective breeding is unlikely to reduce liver abscesses. Instead, the study concluded that the best solution is focusing on practices, including management strategies and interventions, that support rumen health. Further research can determine which management strategies and interventions are most effective in protecting rumen health. This research could offer a promising path to preventing liver abscesses while reducing antibiotic use.

The blood results could also lay the groundwork for a test that detects liver abscesses before cattle are processed. Together, better prevention and earlier detection could improve animal health and welfare, protect producer profits and potentially reduce antibiotic use.

*Beef-on-dairy crossbred heifers are young female cattle that have not yet had a calf and were produced by breeding a dairy cow with a beef-breed bull. The cross is intended to produce calves that are better suited for beef production.

ID: 22-000445