Intact male pigs experience “boar taint,” which causes an unpleasant odor and unsavory taste in the resulting meat. Male pigs are castrated young to prevent boar taint; pain relievers are rarely administered. Castrated piglets show an acute physiological stress response to castration, including increased stress hormone levels, elevated heart rate and demonstrated indicators of pain that can last for four days following the procedure. The European Union has banned the practice of swine castration, but its implementation has been delayed amid challenges to the costs of implementation.
This project has successfully deleted the gene that triggers the release of hormones necessary for sexual maturation in the piglets’ DNA, preventing them from reaching puberty and thus negating the need to castrate the pigs. The next step in this research is determining the commercial viability of castration-free pigs. Since these prototype pigs were created to be permanently prepubescent, the alliance is determining how to breed these pigs without comprising traits like feed efficiency and meat quality. The alliance comprises some of the largest pig genetic companies in the world, possessing the capacity and capabilities needed to supply these permanently prepubescent pigs to pork producers worldwide.
Research is being led by Principal Investigator Tad Sonstegard, Ph.D., Chief Executive and Scientific Officer of Acceligen, Recombinetics’ agriculture division.
“The birth of these castration-free prototype piglets using commercially relevant genetics is just another example of how Acceligen is working to deploy our breeding technologies to help producers better meet the demands of consumers and producers to improve food animal well-being,” said Sonstegard. “The technical expertise and support provided by Hypor and the Foundation for Food & Agriculture Research gives our alliance the capability to meet these demands with the highest standards. Together we will bring the castration-free trait to market and provide solutions to benefit the pork industry,” said Sonstegard.
“At Hendrix Genetics, we are very excited about the birth of the first castration-free piglets. This is an important step to end one of the biggest concerns of the swine industry regarding animal well-being. Within Hypor, Hendrix Genetics’ swine business unit, we are continuously exploring new opportunities to support the pork value chain with innovative and sustainable genetic solutions,” said Luis Prieto Garcia, Managing Director Swine, Hendrix Genetics.
Foundation for Food & Agriculture Research
The Foundation for Food & Agriculture Research (FFAR) builds public-private partnerships to fund bold research addressing big food and agriculture challenges. FFAR was established in the 2014 Farm Bill to increase public agriculture research investments, fill knowledge gaps and complement USDA’s research agenda. FFAR’s model matches federal funding from Congress with private funding, delivering a powerful return on taxpayer investment. Through collaboration and partnerships, FFAR advances actionable science benefiting farmers, consumers and the environment.
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