Egg-Tech Prize Phase II Finalists

Modeling for genomic, blood & microbiological markers for liver abscesses in fed beef cattle

Liver abscesses in cattle are a significant problem for beef and dairy cow producers, jeopardizing animals’ health and costing producers approximately $30 million annually. The condition occurs when bacteria cross from an animal’s gastrointestinal tract into the bloodstream and accumulate in the liver. This research is investigating genetic markers and biomarkers that contribute to the formation of liver abscesses to allow producers to make more informed breeding and management decisions to reduce susceptibility in cattle and reduce reliance on antimicrobial treatments.

Developing Durable Resistance to Fungal Threats in Corn

Corn is one of the most consumed crops globally; however, crop diseases are a major threat to yield. A danger associated with corn consumption is mycotoxins - chemicals produced by certain fungi that grow within the corn plant that cause illness and death in humans and animals. 2Blades is using new genetic tools to develop corn that has strong, long-lasting resistance to these fungi

Understanding liver abscess pathogenesis & risk-factors of feedlot cattle reared in conventional beef versus dairy management systems

Liver abscesses in cattle are a significant problem for beef and dairy cow producers, jeopardizing animals’ health and costing producers approximately $30 million annually. The condition occurs when bacteria cross from an animal’s gastrointestinal tract into the bloodstream and accumulate in the liver. This research is evaluating liver abscess development in feedlot cattle reared in conventional beef versus dairy management systems to provide insight into liver abscess pathogenesis and identify biomarkers that assess the risk of liver abscessation.

Metabolomic analysis of blood plasma to identify unique biomarkers indicative of liver abscesses

Liver abscesses in cattle are a significant problem for beef and dairy cow producers, jeopardizing animals’ health and costing producers approximately $30 million annually. The condition occurs when bacteria cross from an animal’s gastrointestinal tract into the bloodstream and accumulate in the liver. This research is evaluating a comprehensive ‘biochemical fingerprinting’ in blood plasma collected from beef cattle with and without abscesses in the liver. Unique biomolecules in the blood of cattle with liver abscesses can help detect the onset and progression of liver abscesses and can aid evaluating antibiotic alternatives for prevention.

Associations between feeding & management practices of beef-on-dairy cattle from birth to harvest with liver abscesses

Liver abscesses in cattle are a significant problem for beef and dairy cow producers, jeopardizing animals’ health and costing producers approximately $30 million annually. The condition occurs when bacteria cross from an animal’s gastrointestinal tract into the bloodstream and accumulate in the liver. It is commonly controlled by treating entire groups of animals with antibiotics – including healthy ones – because it is difficult to determine which animals are infected. This research is evaluating the associations between feeding and management practices of beef-on-dairy cattle for which it is commonly believed the rate of liver abscesses is two to three times greater than beef cattle crossed with other beef cattle.

Promoting antimicrobial stewardship through improved understanding of how feedlot cattle are classified based on BRD risk

The livestock industry is plagued by bovine respiratory disease (BRD), an infectious condition that can spread through a herd and comprises an estimated 80% of antibiotic treatments. Kansas State University researchers are collecting data to improve understanding of how feedlot cattle are classified based on BRD risk. The data can be used to comprehensively assess health risks and interventions, and as a result, optimize health management strategies for specific cattle populations, improve animal well-being and encourage more efficient antimicrobial use.