FFAR Spurs Tool to Test Bird Flu

Year Awarded  2020

FFAR award amount   $450,000

Total award amount   $715,500

Location   West Lafayette, IN

Matching Funders   Ault Farms, Elanco and Goldstar Cattle

  • Scientific Workforce

FFAR research laid the groundwork for a multi-species HPAI test before the virus jumped beyond birds.

Purdue University researchers developed an innovative paper-based test that rapidly detects highly pathogenic avian influenza (HPAI), commonly known as bird flu.

The test can be effective for a variety of animals, including poultry, cattle, wild birds, rodents and even humans. It requires only an oral or nasal swab that is applied to a paper strip, making it ideal for field use or in areas lacking access to advanced laboratory facilities. This Foundation for Food & Agriculture Research (FFAR)-funded breakthrough stems from earlier research tackling bovine respiratory disease (BRD), a different costly and deadly infection found in cattle.

Dr. Mohit Verma headshot

Because of what I learned about BRD virus testing from my FFAR New Innovator in Food & Agriculture Research Award research, we were already a step ahead in developing a similar test for HPAI. It turns out we started to build the foundation for an HPAI test that’s fast, accurate and easy for farmers and vets to use in the field four years before the world would know that animals beyond birds would be infected with HPAI.

Dr. Mohit Verma
Associate Professor in Purdue’s Department of Agricultural and Biological Engineering and the Weldon School of Biomedical Engineering

Current BRD tests can take days to provide a result, often resulting in delayed treatment or antibiotic overuse.

Dr. Mohit Verma, received a $715,500 New Innovator in Food & Agriculture Research Award in 2020 to develop a rapid diagnostic test for BRD, a common disease affecting cattle that results in nearly $1 billion in annual losses for the U.S. beef industry. Traditional methods to detect the virus are often subjective and limited in accuracy.

Verna’s research to improve BRD testing was awarded several years before the recent HPAI outbreak. Accurate and efficient tests for HPAI are critical to properly control the spread of this highly contagious and deadly virus.

Verma’s BRD research led to a user-friendly, low-cost test that can detect the virus in under 60 minutes. This research laid the groundwork for a similar HPAI test.

The BRD test can assist veterinarians and cattle producers in determining the most effective methods to treat and prevent the disease.

Verma’s research team used these research results to introduce and validate a new paper-based test that could quickly, affordably and reliably detect HPAI viruses.

Verma and four co-authors published the details of their HPAI test in Scientific Reports. This work was funded in part by FFAR, with additional funding from the National Institutes of Health (NIH) and the Clinical and Translational Sciences Award from the NIH’s National Center for Advancing Translational Sciences.

Portrait of Angela Records.

One of the most powerful aspects of scientific research is its ability to generate insights that extend beyond the original question. Findings from Verma’s original FFAR grant, aimed at BRD challenges, are now helping us better understand a different — more widespread and critical — problem [HPAI]. This kind of cross-cutting impact is exactly what we hope for when we invest in innovative science to support U.S. farmers.

Angela Records, Ph.D.
Chief Scientific Officer

See this research in action

Pen-side Test for Bovine Respiratory Disease

Video courtesy of Purdue University College of Agriculture

Scientific Publications